2,1,3-Benzothiadiazol-5-ylmethanol → 2,1,3-Benzothiadiazole-5-carbaldehyde

HRID 1357750

反応式

HRID 1357750 の反応式
[OH:1][CH2:2][C:3]1[CH:11]=[CH:10][C:6]2=[N:7][S:8][N:9]=[C:5]2[CH:4]=1>C(Cl)(Cl)Cl.[O-2].[O-2].[Mn+4]>[N:7]1[S:8][N:9]=[C:5]2[CH:4]=[C:3]([CH:2]=[O:1])[CH:11]=[CH:10][C:6]=12

参加物

4

反応物 1

HCID 27762942,1,3-Benzothiadiazol-5-ylmethanol

生成物 1

HCID 27762902,1,3-Benzothiadiazole-5-carbaldehyde収率 72.3%

試薬・触媒・溶媒 2

HCID 178418406HCID 178418406、化合物触媒HCID 6212Chloroform溶媒

実験手順

5-Hydroxymethylbenzo-2, 1,3-thiadiazole (2.6 g, 16 mmol) and manganese dioxide (6.0 g, 64 mmol) in chloroform (150 mL) were stirred at room temperature overnight. The reaction mixture was filtered off and the filtrate was evaporated to provide 1.9 g of the title compound.

後処理

  1. filtrationThe reaction mixture was filtered off
  2. customthe filtrate was evaporated

出典と根拠

ORDレコード
ord-d6214540b07f41f691e40f83b9cf0f40
出典データセット
uspto-grants-2003_07
特許番号
US06593335B1

関連ノート

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