Isopropylamine → 2-Amino-N-isopropylbenzamide

HRID 1362848

反応式

HRID 1362848 の反応式
[C:1]12[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=1)[NH:6]C(=O)[O:4][C:2]2=O.[CH:13]([NH2:16])([CH3:15])[CH3:14]>O>[NH2:6][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:1]=1[C:2]([NH:16][CH:13]([CH3:15])[CH3:14])=[O:4]

参加物

4

反応物 2

HCID 6363IsopropylamineHCID 8359Isatoic Anhydride

生成物 1

HCID 944112-Amino-N-isopropylbenzamide収率 77.1%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A round-bottomed flask was charged with isatoic anhydride (5.0 g, 0.030 mol) and 30 mL water. Isopropylamine (4.64 mL, 0.049 mol) was added slowly to the reaction mixture. The product precipitated from the reaction mixture. After 1 h, the reaction mixture was filtered and washed with water to give 4.12 g (71% yield) of a white solid

後処理

  1. customThe product precipitated from the reaction mixture
  2. filtrationthe reaction mixture was filtered
  3. washwashed with water

出典と根拠

ORDレコード
ord-7fc24b27a8664e549d66df96405fa8cf
出典データセット
uspto-grants-2011_02
特許番号
US07884098B2

関連ノート

読み込み中…