L-Tryptophan → L-(-)-Tryptophanol

HRID 1364094

反応式

HRID 1364094 の反応式
[NH2:1][C@H:2]([C:13](O)=[O:14])[CH2:3][C:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[NH:6][CH:5]=1>CO[2H]>[NH2:1][C@@H:2]([CH2:3][C:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[NH:6][CH:5]=1)[CH2:13][OH:14]

参加物

3

反応物 1

HCID 6305L-Tryptophan

生成物 1

HCID 6951149L-(-)-Tryptophanol収率 92%

試薬・触媒・溶媒 1

HCID 123113Methan(2H)ol溶媒

実験手順

The title compound was prepared from (S)-tryptophan according to Method D and was isolated as a solid in 92% yield. δH (MeOD-d3) 7.46 (1H, d, J 7.9 Hz), 7.21 (1H, d, J 8.0 Hz), 6.96 (3H, m), 3.79 (1H, dd, J 11.3 and 3.6 Hz), 3.54 (1H, dd, J 11.3 and 6.2 Hz), 3.05 (1H, m), 2.80 (1H, m), 2.61 (1H, m). Note: exchangeable protons not evident in MeOD.

後処理

  1. customwas isolated as a solid in 92% yield

出典と根拠

ORDレコード
ord-007bb295874144248d771a25b8014a86
出典データセット
uspto-grants-2011_02
特許番号
US07888344B2

関連ノート

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