Triethylamine → 2-Ethyl-2-methacryloyloxyadamantane

HRID 1369358

反応式

HRID 1369358 の反応式
[CH2:1]([C:3]1([OH:13])[CH:10]2[CH2:11][CH:6]3[CH2:7][CH:8]([CH2:12][CH:4]1[CH2:5]3)[CH2:9]2)[CH3:2].C(N(CC)CC)C.[C:21](Cl)(=[O:25])[C:22]([CH3:24])=[CH2:23]>CC(CC(C)C)=O>[C:21]([O:13][C:3]1([CH2:1][CH3:2])[CH:4]2[CH2:12][CH:8]3[CH2:7][CH:6]([CH2:11][CH:10]1[CH2:9]3)[CH2:5]2)(=[O:25])[C:22]([CH3:24])=[CH2:23]

参加物

5

反応物 3

HCID 8471TriethylamineHCID 13528Methacryloyl chlorideHCID 44019512-Ethyl-2-adamantanol

生成物 1

HCID 98136452-Ethyl-2-methacryloyloxyadamantane収率 60%

試薬・触媒・溶媒 1

HCID 7909Methyl Isobutyl Ketone溶媒

反応条件

温度
90 °C

実験手順

180 g of 2-Ethyl-2-adamantanol, 303 g of triethylamine and 500 g of methylisobutyl ketone were mixed by stirring at 90° C. While stirring, 157 g of methacrylic acid chloride was added dropwise to the mixture. After completion of the dropwise addition, the mixture was further stirred for 72 hours. Then, extraction and distillation were conducted to obtain 2-ethyl-2-adamantyl methacrylate at the yield of 60%.

後処理

  1. stirringWhile stirring
  2. additionAfter completion of the dropwise addition
  3. stirringthe mixture was further stirred for 72 hours
  4. extractionThen, extraction and distillation

出典と根拠

ORDレコード
ord-9a8617f7ceab4cba9d7d1e46a274944a
出典データセット
uspto-grants-2003_06
特許番号
US06579659B2

関連ノート

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