Methanol → 3-(Allyloxy)phenol
反応式
C([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][CH2:12][CH:13]=[CH2:14])[CH:6]=1)(=O)C.[OH-].[Na+].CO>C1COCC1>[CH2:12]([O:11][C:7]1[CH:6]=[C:5]([OH:4])[CH:10]=[CH:9][CH:8]=1)[CH:13]=[CH2:14]参加物
5
実験手順
The product from Example 61A (7.19 g, 37.4 mmoles) in THF (30 mL) was treated with 4N NaOH (19 mL, 75 mmoles) and MeOH (5 mL). After one hour, the reaction mixture was concentrated under reduced pressure. The residue was dissolved in ethyl acetate, washed with aqueous NH4Cl, brine, dried (Na2SO4), filtered, and the filtrate concentrated under reduced pressure to provide the title compound without further purification.
後処理
- concentrationthe reaction mixture was concentrated under reduced pressure
- dissolutionThe residue was dissolved in ethyl acetate
- washwashed with aqueous NH4Cl, brine
- dry with materialdried (Na2SO4)
- filtrationfiltered
- concentrationthe filtrate concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-83b92bd422474d3b90f45bf086b1dfbf
- 出典データセット
- uspto-grants-2003_06
- 特許番号
- US06583180B2
反応ノート
読み込み中…