HCID 12094927、化合物 → HCID 12094928、化合物

HRID 1373989ノート

反応式

HRID 1373989 の反応式
[C:1]1([C:6]2[CH:7]=[C:8]([CH2:12][OH:13])[CH:9]=[CH:10][CH:11]=2)[CH2:5][CH2:4][CH2:3][CH:2]=1>O=[Mn]=O.C(Cl)(Cl)Cl>[C:1]1([C:6]2[CH:7]=[C:8]([CH:9]=[CH:10][CH:11]=2)[CH:12]=[O:13])[CH2:5][CH2:4][CH2:3][CH:2]=1

参加物

4

反応物 1

HCID 12094927HCID 12094927、化合物

生成物 1

HCID 12094928HCID 12094928、化合物収率 76.2%

試薬・触媒・溶媒 2

HCID 14801Manganese dioxide触媒HCID 6212Chloroform溶媒

反応条件

温度
60 °C

実験手順

1.35 g (8 mmol) of (3-cyclopenten-1-ylphenyl)methanol (5a) and 80 ml of chloroform are introduced into a round-bottomed flask. 6.8 g of MnO2 are then added and the suspension is heated at 60° C. for 2 hours. The mixture is filtered in the hot state, the precipitate washed with chloroform and then the filtrate concentrated under reduced pressure. The title product (1.05 g) is obtained in the form of a yellow oil which is used in the next step without further purification.

後処理

  1. filtrationThe mixture is filtered in the hot state
  2. washthe precipitate washed with chloroform
  3. concentrationthe filtrate concentrated under reduced pressure

出典と根拠

ORDレコード
ord-91e66b52a2694e669d576b4da976f71f
出典データセット
uspto-grants-2007_01
特許番号
US07163957B2

反応ノート

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