2-Chloroethyl vinyl ether → 1-Cyclohexyl-4-[2-(ethenyloxy)ethoxy]benzene

HRID 1385856

反応式

HRID 1385856 の反応式
[CH:1]1([C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH:14]([O:16][CH2:17][CH2:18]Cl)=[CH2:15].[OH-].[Na+].C(N(CC)CC)C>C1(C)C=CC=CC=1.[Br-].C([N+](CCCC)(CCCC)CCCC)CCC>[CH:14]([O:16][CH2:17][CH2:18][O:13][C:10]1[CH:9]=[CH:8][C:7]([CH:1]2[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]2)=[CH:12][CH:11]=1)=[CH2:15]

参加物

7

反応物 4

HCID 80742-Chloroethyl vinyl etherHCID 8471TriethylamineHCID 143274-CyclohexylphenolHCID 14798Sodium Hydroxide

生成物 1

HCID 220116871-Cyclohexyl-4-[2-(ethenyloxy)ethoxy]benzene

試薬・触媒・溶媒 2

HCID 74236Tetrabutylammonium Bromide触媒HCID 1140Toluene溶媒

実験手順

In 300 ml of toluene, 83.1 g (0.5 mol) of p-cyclohexylphenol was dissolved, and then 150 g of 2-chloroethyl vinyl ether, 25 g of sodium hydroxide, 5 g of tetrabutylammonium bromide and 60 g of triethylamine were added thereto, followed by a reaction at 120° C. for 5 hours. The reaction solution was washed with water, and excess chloroethyl vinyl ether and toluene were removed by distillation. The resulting oil was purified by distillation under reduced pressure to obtain 4-cyclohexylphenoxyethyl vinyl ether.

後処理

  1. customfollowed by a reaction at 120° C. for 5 hours
  2. washThe reaction solution was washed with water, and excess chloroethyl vinyl ether and toluene
  3. customwere removed by distillation
  4. distillationThe resulting oil was purified by distillation under reduced pressure

出典と根拠

ORDレコード
ord-f79c2e2862cf48299d8cfaaeb44f3d7b
出典データセット
uspto-grants-2001_07
特許番号
US06265135B1

関連ノート

読み込み中…