Thionyl Chloride → 2-(4-ethoxyphenyl)acetyl Chloride

HRID 1385894

反応式

HRID 1385894 の反応式
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([CH2:10][C:11]([OH:13])=O)=[CH:6][CH:5]=1)[CH3:2].S(Cl)([Cl:16])=O>>[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([CH2:10][C:11]([Cl:16])=[O:13])=[CH:6][CH:5]=1)[CH3:2]

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 78631Benzeneacetic acid, 4-ethoxy-

生成物 1

HCID 116297822-(4-ethoxyphenyl)acetyl Chloride

実験手順

50 g (0.28 mol) of 4-ethoxyphenylacetic acid were treated with 50 ml of thionyl chloride and the mixture was stirred for 24 hours at room temperature. Excess thionyl chloride was removed in vacuo and the residue was distilled under a high vacuum. This gave 39 g (71% of theory) of an oil (boiling point 110° C./53.3 Pa).

後処理

  1. customExcess thionyl chloride was removed in vacuo
  2. distillationthe residue was distilled under a high vacuum

出典と根拠

ORDレコード
ord-ab873478ff5c4224a1fffcfd1c5328c0
出典データセット
uspto-grants-2001_07
特許番号
US06265398B1

関連ノート

読み込み中…