Diisopropyl Ether → 2-[2-(2,4-Dichlorophenyl)ethyl]oxirane
反応式
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH2:9][CH2:10][CH:11]([CH2:13]Cl)[OH:12].[OH-].[Na+].O(C(C)C)C(C)C>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH2:9][CH2:10][CH:11]1[CH2:13][O:12]1参加物
4
実験手順
A solution of 87 parts of 2,4-dichloro-α-(chloromethyl)-benzenepropanol in 144 parts of concentrated sodium hydroxide solution and 350 parts of 2,2'-oxybispropane is stirred overnight at room temperature. The product is extracted with 2,2'-oxybispropane. The extract is washed with water, dried, filtered and evaporated. The oily residue is distilled, yielding [2-(2,4-dichlorophenyl)ethyl]oxirane; bp. 90°-98° C. at 0.01 mm. pressure.
後処理
- extractionThe product is extracted with 2,2'-oxybispropane
- washThe extract is washed with water
- customdried
- filtrationfiltered
- customevaporated
- distillationThe oily residue is distilled
出典と根拠
- ORDレコード
- ord-9780b98567144e14a2f152c799d60101
- 出典データセット
- uspto-grants-1979_02
- 特許番号
- US04139540
反応ノート
読み込み中…