Methyl iodide → N,N-Diethyl-2-methoxy-N-methylethan-1-aminium iodide

HRID 1392804ノート

反応式

HRID 1392804 の反応式
[CH3:1][O:2][CH2:3][CH2:4][N:5]([CH2:8][CH3:9])[CH2:6][CH3:7].[CH3:10][I:11]>O1CCCC1>[I-:11].[CH3:1][O:2][CH2:3][CH2:4][N+:5]([CH2:8][CH3:9])([CH2:6][CH3:7])[CH3:10]

参加物

4

反応物 2

HCID 6328Methyl iodideHCID 113555002-methoxyethyldiethylamine

生成物 1

HCID 71374868N,N-Diethyl-2-methoxy-N-methylethan-1-aminium iodide

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

Next, 8.24 g of the 2-methoxyethyldiethylamine was dissolved in 10 ml of tetrahydrofuran (Wako Pure Chemical Industries, Ltd.), then 4.0 ml of methyl iodide (Wako Pure Chemical Industries, Ltd.) was added under ice cooling. After 30 minutes, the mixture was removed from the ice bath and stirred overnight at room temperature. The solvent in the resulting reaction solution was subsequently driven off by vacuum distillation, and the resulting solids were recrystallized from an ethanol (Wako Pure Chemical Industries, Ltd.)—tetrahydrofuran system, yielding 16 g of 2-methoxyethyldiethylmethylammonium iodide.

後処理

  1. customthe mixture was removed from the ice bath
  2. customThe solvent in the resulting reaction solution
  3. distillationwas subsequently driven off by vacuum distillation
  4. customthe resulting solids were recrystallized from an ethanol (Wako Pure Chemical Industries, Ltd.)—tetrahydrofuran system

出典と根拠

ORDレコード
ord-f96cca6dbd3f492f8e0540bec9d44b22
出典データセット
uspto-grants-2008_03
特許番号
US07342769B2

反応ノート

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