Mesitylene → 5-Allyl-6-chloroindan-4-ol
反応式
C([O:4][C:5]1[CH:13]=[C:12]([Cl:14])[CH:11]=[C:10]2[C:6]=1[CH2:7][CH2:8][CH2:9]2)C=C.[C:15]1(C)[CH:20]=C(C)C=C(C)[CH:16]=1>>[CH2:20]([C:13]1[C:12]([Cl:14])=[CH:11][C:10]2[CH2:9][CH2:8][CH2:7][C:6]=2[C:5]=1[OH:4])[CH:15]=[CH2:16]参加物
3
実験手順
Treatment of 4-(allyloxy)-6-chloroindane (8.0 g, 0.038 mol) in refluxing mesitylene (270 mL) generally according to the procedure described for Intermediate 1 afforded 4.5 g (56%) of 5-allyl-6-chloroindan-4-ol as a colorless oil which solidified into a white solid upon standing. mp 37-39° C.; Anal. calcd. for C12H13ClO.0.1H2O: C, 68.48; H, 6.32. Found: C, 68.54; H, 6.29.
出典と根拠
- ORDレコード
- ord-a22c5adcc1c84f2c827b68d9447ff539
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07728155B2
反応ノート
読み込み中…