Formaldehyde → 2-{(5-{[N-methyl-N-propargylamino]methyl}-2-furyl)methylthio}ethylamine
反応式
[CH2:1](O)[C:2]1[O:6][CH:5]=[CH:4][CH:3]=1.Cl.[CH3:9][NH:10][CH2:11][C:12]#[CH:13].[CH2:14]=O.Cl.[NH2:17][CH2:18][CH2:19][SH:20]>>[CH3:9][N:10]([CH2:1][C:2]1[O:6][C:5]([CH2:14][S:20][CH2:19][CH2:18][NH2:17])=[CH:4][CH:3]=1)[CH2:11][C:12]#[CH:13]参加物
5
実験手順
The reaction of furfuryl alcohol and N-methylpropargylamine hydrochloride with paraformaldehyde according to the general procedure of J. Chem. Soc., 4728 (1958), and treatment of the product with cysteamine hydrochloride followed by neutralization, produces 2-{(5-{[N-methyl-N-propargylamino]methyl}-2-furyl)methylthio}ethylamine. When the latter product is reacted with 1,1-bis(methylthio)-2-nitroethylene and then with propargylamine according to the general procedure of Example 1, the title compound is produced.
出典と根拠
- ORDレコード
- ord-f7c85633fbd54fdcb9f18da8095219b5
- 出典データセット
- uspto-grants-1980_05
- 特許番号
- US04203909
反応ノート
読み込み中…