HCID 86632904、化合物 → HCID 68735949、化合物

HRID 1398898ノート

反応式

HRID 1398898 の反応式
[F:1][C:2]1[CH:7]=[C:6]([N+:8]([O-])=O)[C:5]([NH:11][CH2:12][CH2:13][CH2:14][OH:15])=[C:4]([N+:16]([O-])=O)[CH:3]=1>O1CCCC1.[Pd]>[NH2:16][C:4]1[CH:3]=[C:2]([F:1])[CH:7]=[C:6]([NH2:8])[C:5]=1[NH:11][CH2:12][CH2:13][CH2:14][OH:15]

参加物

4

反応物 1

HCID 86632904HCID 86632904、化合物

生成物 1

HCID 68735949HCID 68735949、化合物収率 100%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 8028Tetrahydrofuran溶媒

実験手順

A solution of 3-[(4-fluoro-2,6-dinitrophenyl)amino]propan-1-ol (3.59 g, 13.8 mmol) in tetrahydrofuran (140 mL) was stirred in the presence of 10% palladium on carbon (50% wet; 720 mg) under'hydrogen atmosphere at room temperature for 1.5 h. The catalyst was removed by filtration, and the filtrate was concentrated in vacuo to give the title compound as a pale brown oil (2.75 g, 13.8 mmol, 100%).

後処理

  1. customThe catalyst was removed by filtration
  2. concentrationthe filtrate was concentrated in vacuo

出典と根拠

ORDレコード
ord-8539c31e68bb4624b76ee5bc5f878ad0
出典データセット
uspto-grants-2014_12
特許番号
US08901141B2

反応ノート

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