Pyridine → 1-Chloro-1-(p-prenylphenyl)ethane
反応式
[CH2:1]([C:6]1[CH:11]=[CH:10][C:9]([CH:12](O)[CH3:13])=[CH:8][CH:7]=1)[CH:2]=[C:3]([CH3:5])[CH3:4].N1C=CC=CC=1.S(Cl)([Cl:23])=O>C1C=CC=CC=1>[Cl:23][CH:12]([C:9]1[CH:10]=[CH:11][C:6]([CH2:1][CH:2]=[C:3]([CH3:5])[CH3:4])=[CH:7][CH:8]=1)[CH3:13]参加物
5
実験手順
To a solution of 9.5 g of 1-(p-prenylphenyl)-ethanol, 4.0 ml of pyridine and 60 ml of benzene, a solution of 5.9 g of thionyl chloride in 10 ml of benzene was added dropwise at 0°-5° C. with stirring. After stirring at room temperature for an hour, the reaction mixture was washed with water, aqueous sodium hydrogen carbonate and water successively and dried. Removal of the benzene gave 10.1 g of 1-chloro-1-(p-prenylphenyl)ethane.
後処理
- stirringAfter stirring at room temperature for an hour
- washthe reaction mixture was washed with water, aqueous sodium hydrogen carbonate and water successively
- customdried
- customRemoval of the benzene
出典と根拠
- ORDレコード
- ord-786247acd8e441f597923049a809feea
- 出典データセット
- uspto-grants-1981_02
- 特許番号
- US04251543
反応ノート
読み込み中…