Acetoacetic Acid → Acetic Acid

HRID 1415442ノート

反応式

HRID 1415442 の反応式
[O:1]1[CH2:5][CH2:4][CH2:3][CH:2]1[CH2:6][C:7]([OH:9])=[O:8].C(OCCCCOC(=O)C)(=O)C.CC(CC(O)=O)=O.C(OC(OC(=O)C)CCC)(=O)C>O>[O:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[C:7]([OH:9])(=[O:8])[CH3:6]

参加物

7

反応物 4

HCID 96Acetoacetic AcidHCID 69410Butylene glycol diacetateHCID 182019Butanediol, diacetateHCID 2287262-(Oxolan-2-yl)acetic acid

生成物 2

HCID 176Acetic Acid収率 89%HCID 8028Tetrahydrofuran収率 47%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

The tube reactor is charged with 88.1 grams of Linde 13X zeolite (150 pellets, pretreated at 200° C. with a tetrahydrofuran-acetic acid vapor mixture) and maintained at 190°-230° C. while 50.0 grams of 1,4-butanediol diacetate and 60 ml. of water are copassed, as in Examples 1-3, over a 1 hour period. The effluent is recycled three times until the diacetate is essentially converted. Quantitative glpc analysis of the final effluent shows the presence of 0.4 grams of butanediol diacetate (1% recovery), 9.5 grams of tetrahydrofuran (47% yield) and 30.4 grams of acetic acid (89% yield). A considerable amount of low boiling material is produced using this method.

出典と根拠

ORDレコード
ord-2dfa87c741ac498ba5b1cd06c1ec92e2
出典データセット
uspto-grants-1977_01
特許番号
US04005113

反応ノート

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