Ethylene Glycol → HCID 57081597、化合物

HRID 1418364

反応式

HRID 1418364 の反応式
[CH:1]([C:3]1[CH:10]=[CH:9][CH:8]=[CH:7][C:4]=1[CH:5]=[O:6])=[CH2:2].C[Si](Cl)(C)C.[CH2:16](O)[CH2:17][OH:18]>C(=O)(O)[O-].[Na+]>[CH2:17]1[O:18][CH:5]([C:4]2[CH:7]=[CH:8][CH:9]=[CH:10][C:3]=2[CH:1]=[CH2:2])[O:6][CH2:16]1

参加物

5

反応物 3

HCID 174Ethylene GlycolHCID 6397ChlorotrimethylsilaneHCID 39391Benzaldehyde, 2-ethenyl-

生成物 1

HCID 57081597HCID 57081597、化合物

試薬・触媒・溶媒 1

HCID 516892Sodium Bicarbonate溶媒

実験手順

A mixture of 2-vinylbenzaldehyde (2.9 g, 22 mmol) and trimethylsilyl chloride (11 ml) in ethylene glycol (95 ml) was stirred for 16 h, diluted with saturated sodium bicarbonate solution, extracted with ether, dried over sodium sulphate and evaporated to afford a colourless oil (2.7 g), MS (+EI) 176 (M+), 1H NMR (CDCl3) 7.57 (1H, m), 7.53 (1H, dd, J1.5, 7.5 Hz), 7.36-7.30 (2H, m), 7.14 (1H, dd, J11, 17.4 Hz), 6.04 (1H, s) 5.69 (1H, dd, J1.3, 17.4 Hz), 5.34 (1H, dd, J1.3, 11.0 Hz), 4.18-4.04 (2H, m), 3.77-3.65 (2H, m).

後処理

  1. extractionextracted with ether
  2. dry with materialdried over sodium sulphate
  3. customevaporated

出典と根拠

ORDレコード
ord-af51443a925a48a791f16128fb1ca950
出典データセット
uspto-grants-1999_03
特許番号
US05883102

関連ノート

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