Hydrochloric Acid → Allyl 4-bromobutyrate
反応式
[Br:1][CH2:2][CH2:3][CH2:4][C:5](Cl)=[O:6].C([OH:11])C=C.N1C=C[CH:15]=[CH:14][CH:13]=1.Cl>ClCCl>[Br:1][CH2:2][CH2:3][CH2:4][C:5]([O:6][CH2:13][CH:14]=[CH2:15])=[O:11]参加物
6
実験手順
4-Bromobutryl chloride (18.6 g) was treated with allyl alcohol (5.8 g) in the presence of pyridine (8 g) in dry dichloromethane at 0° C. for 0.5 hours. The solution was treated with aqueous HCl and warmed to room temperature. The organic layer was separated, washed with saturated aqueous brine, dried (MgSO4) and evaporated to give the title compound as a colourless oil, 19.7 g, 95% yield
後処理
- customThe organic layer was separated
- washwashed with saturated aqueous brine
- dry with materialdried (MgSO4)
- customevaporated
出典と根拠
- ORDレコード
- ord-9190722aae10416280c7065235af5f40
- 出典データセット
- uspto-grants-2000_06
- 特許番号
- US06071899
反応ノート
読み込み中…