Methyl iodide → HCID 178503559、化合物

HRID 1429184

反応式

HRID 1429184 の反応式
[CH3:1]I.[NH:3]1[C:10](=[O:11])[CH2:9][C:7](=[O:8])[NH:6][C:4]1=[S:5]>CCO.[OH-].[Na+].O>[CH3:1][S:5][C:4]1[N:6]=[C:7]([OH:8])[CH:9]=[C:10]([OH:11])[N:3]=1

参加物

6

反応物 2

HCID 6328Methyl iodideHCID 2723628Thiobarbituric acid

生成物 1

HCID 178503559HCID 178503559、化合物

試薬・触媒・溶媒 3

HCID 702Ethanol溶媒HCID 962Water溶媒HCID 14798Sodium Hydroxide溶媒

実験手順

Methyl iodide (32.64 g, 220 mmol) was added dropwise to a suspension of thiobarbituric acid (29 g, 200 mmol) in EtOH (300 ml) and 2M NaOH solution in water (110 ml) at room temperature. The mixture was stirred at room temperature overnight and then stirred for two hours at 60° C. The ethanol was removed, water was added and the mixture was allowed to stay for 2 hours on an ice bath. The solid title compound was filtered of, washed with ice cold water and dried (30 g, 95%).

後処理

  1. stirringstirred for two hours at 60° C
  2. customThe ethanol was removed
  3. additionwater was added
  4. waitto stay for 2 hours on an ice bath
  5. filtrationThe solid title compound was filtered of,
  6. washwashed with ice cold water
  7. customdried (30 g, 95%)

出典と根拠

ORDレコード
ord-70a84a861a8c4482820164954375ee84
出典データセット
uspto-grants-2015_01
特許番号
US08937080B2

関連ノート

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