1,8-Dihydroxyanthraquinone → HCID 15855945、化合物

HRID 1440949

反応式

HRID 1440949 の反応式
[OH:1][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][C:12]=3[OH:17])[C:7](=[O:18])[C:6]=2[CH:5]=[CH:4][CH:3]=1.[CH2:19](OS(C1C=CC(C)=CC=1)(=O)=O)[CH2:20][CH2:21][CH3:22].C(=O)([O-])[O-].[Na+].[Na+]>ClC1C=CC=CC=1Cl>[CH2:19]([O:1][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][C:12]=3[O:17][CH2:15][CH2:2][CH2:3][CH3:4])[C:7](=[O:18])[C:6]=2[CH:5]=[CH:4][CH:3]=1)[CH2:20][CH2:21][CH3:22]

参加物

5

反応物 3

HCID 29501,8-DihydroxyanthraquinoneHCID 10340Sodium CarbonateHCID 13066Butyl-p-toluenesulfonate

生成物 1

HCID 15855945HCID 15855945、化合物収率 154.4%

試薬・触媒・溶媒 1

HCID 72391,2-Dichlorobenzene溶媒

実験手順

A suspension of 1,8-dihydroxyanthraquinone (35.0 g, 0.14 mol), butyltosylate (93 g, 0.6 mol), and sodium carbonate (38 g, 0.36 mol) in 700 mL of o-dichlorobenzene was heated at reflux for 6 days. The mixture was cooled to room temperature, filtered, and the solvent was removed by steam distillation. The residue was recrystallized from isopropanol to provide 38.1 g (74% yield) of 1,8-dibutoxyanthraquinone, which has the structural formula: ##STR48##

後処理

  1. temperaturewas heated
  2. temperatureat reflux for 6 days
  3. filtrationfiltered
  4. customthe solvent was removed by steam distillation
  5. customThe residue was recrystallized from isopropanol

出典と根拠

ORDレコード
ord-eea3f8a493484bff83e22e3a782f89d4
出典データセット
uspto-grants-1996_03
特許番号
US05501821

関連ノート

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