Methyl iodide → HCID 68821354、化合物
反応式
[CH3:1][C:2]1[C:10]2[S:9](=[O:12])(=[O:11])[N:8]=[CH:7][NH:6][C:5]=2[S:4][CH:3]=1.[C:13](=O)([O-])[O-].[K+].[K+].IC>C(#N)C>[CH3:13][N:6]1[C:5]2[S:4][CH:3]=[C:2]([CH3:1])[C:10]=2[S:9](=[O:12])(=[O:11])[N:8]=[CH:7]1参加物
5
反応条件
- 温度
- 65 °C
実験手順
150 mg of the compound obtained in Step A above are suspended in 5 ml of acetonitrile. 300 mg of potassium carbonate and 0.15 ml of iodomethane are added thereto. The reaction mixture is heated at 65° C. for 30 minutes, with stirring. After evaporation of the solvents under reduced pressure, the residue is taken up in 5 ml of water and then collected by filtration, washed with water and dried.
後処理
- customAfter evaporation of the solvents under reduced pressure
- filtrationcollected by filtration
- washwashed with water
- customdried
出典と根拠
- ORDレコード
- ord-57a84ff683de44b3b0c3dea3656a3a01
- 出典データセット
- uspto-grants-2009_01
- 特許番号
- US07476668B2
反応ノート
読み込み中…