N-bromobutanimide → 5-Bromo-2,2-diphenyl-1,3-benzodioxol

HRID 1461081ノート

反応式

HRID 1461081 の反応式
[Br:1]N1C(=O)CCC1=O.[C:9]1([C:15]2([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[O:19][C:18]3[CH:20]=[CH:21][CH:22]=[CH:23][C:17]=3[O:16]2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>C(Cl)(Cl)Cl>[Br:1][C:22]1[CH:21]=[CH:20][C:18]2[O:19][C:15]([C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=3)([C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=3)[O:16][C:17]=2[CH:23]=1

参加物

4

反応物 2

HCID 67184N-bromobutanimideHCID 3439592,2-Diphenyl-1,3-benzodioxole

生成物 1

HCID 223195155-Bromo-2,2-diphenyl-1,3-benzodioxol

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

実験手順

18.75 g of N-bromosuccinimide are added to a solution of 27.4 g of 2,2-diphenyl-1,3-benzodioxol in 80 ml of chloroform and the mixture was boiled at reflux for 20 hours. The reaction mixture was cooled and the separated succinimide was filtered off. The filtrate was washed with water, dried over sodium sulphate and the solvent was removed in a vacuum. By crystallization of the residue from ethanol, there was obtained 5-bromo-2,2-diphenyl-1,3-benzodioxol as white crystals of melting point 88°-89° C.

後処理

  1. temperatureat reflux for 20 hours
  2. temperatureThe reaction mixture was cooled
  3. filtrationthe separated succinimide was filtered off
  4. washThe filtrate was washed with water
  5. dry with materialdried over sodium sulphate
  6. customthe solvent was removed in a vacuum
  7. customBy crystallization of the residue from ethanol

出典と根拠

ORDレコード
ord-1f40e0ed99974a8d8d8867f12beacd33
出典データセット
uspto-grants-1991_12
特許番号
US05073550

反応ノート

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