Isopropanol → Isopropyl 2-cyanoethyl(ethyl)phosphinate
反応式
[CH:1]([O:4][P:5]([CH2:7][CH3:8])[OH:6])([CH3:3])[CH3:2].[C:9](#[N:12])[CH:10]=[CH2:11].C(O)(C)C.[Na]>>[C:9]([CH2:10][CH2:11][P:5]([CH2:7][CH3:8])(=[O:6])[O:4][CH:1]([CH3:3])[CH3:2])#[N:12]参加物
5
実験手順
To 34 g of ethylphosphonous acid-isopropylester and 16.45 ml of acrylonitrile is added with stirring 40 ml of isopropanol containing 0.25 mol of sodium isopropylate. The reaction is exothermic. After 1 hour stirring at 20° the mixture is fractionated. There is obtained isopropyl 2-cyanoethyl(ethyl)phosphinate as a colorless oil, b.p. 102°-104°/10 Pa.
出典と根拠
- ORDレコード
- ord-126b0e7a717b4ae090772ad26341cc2f
- 出典データセット
- uspto-grants-1994_04
- 特許番号
- US05300679
反応ノート
読み込み中…