反応式
[FH:1].Cl[C:3]([O:5][C:6]1[C:11]([CH3:12])=[CH:10][CH:9]=[CH:8][C:7]=1[CH3:13])=[O:4]>FC(F)(Cl)C(F)(Cl)Cl>[CH3:13][C:7]1[CH:8]=[CH:9][CH:10]=[C:11]([CH3:12])[C:6]=1[F:1].[F:1][C:3]([O:5][C:6]1[C:11]([CH3:12])=[CH:10][CH:9]=[CH:8][C:7]=1[CH3:13])=[O:4]参加物
5
反応条件
- 温度
- 160 °C
実験手順
70 ml of hydrogen fluoride and 200 ml of 1,1,2-trifluoro-1,2,2-trichloroethane were placed at 0° C. in a stainless steel autoclave and 100 g of 2,6-dimethylphenyl chloroformate were added dropwise. The autoclave was sealed and heated at a maximum temperature of 160° C. for 5 hours, the pressure of the gases formed being released at 30 bar. The reaction mixture was worked up as described in Example 9. 2,6-Dimethylfluorobenzene was obtained in a yield of 30% and 2,6-dimethylphenyl fluoroformate in a yield of 40%. The latter can be added to a new batch for the preparation of 2,6-dimethylfluorobenzene (see Example 15).
後処理
- additionwere added dropwise
- customThe autoclave was sealed
- customthe pressure of the gases formed
出典と根拠
- ORDレコード
- ord-641bd3e7226b4957978ba064149e165e
- 出典データセット
- uspto-grants-1994_04
- 特許番号
- US05306849
関連ノート
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