2-Methoxythiophene → 2-(5-Methoxythiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

温度

25 °C

Prepared from 2-methoxythiophene (4j, 114.2 mg, 1.00 mmol, 1.00 equiv), catBH (240 mg, 2.00 mmol, 2.00 equiv), N,N,4-trimethylaniline (1f, 13.5 mg, 0.10 mmol, 0.10 equiv), norbornene (94.0 mg, 1.00 mmol, 1.00 equiv), and B(C6F5)3 (51.2 mg, 0.10 mmol, 0.10 equiv) according to GP 3. The title compound was purified by flash column chromatography using cyclohexane/EtOAc/Et3N (30/1/1) as eluent to afford 6j[S5] (96.8 mg, 40%) as a colorless liquid.

ORDレコード

ord-9284ce38474e4c6197f167142a799d26

出典データセット

Borylation dataset from Roche

DOI

10.1002/anie.201611536