Ethyl 2-thenoate → Ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carboxylate

HRID 1490708

反応式

HRID 1490708 の反応式
CCOC(=O)c1cccs1>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCOC1.CC(C)(C)O.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].O=c1ccc2cccc(-c3ccc(-c4ccccn4)nc3)c2[nH]1.[Ir].[Ir].[K]>CCOC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)s1

参加物

7

反応物 1

HCID 76052Ethyl 2-thenoate

生成物 1

HCID 46739336Ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carboxylate収率 93%

試薬・触媒・溶媒 5

HCID 2733548Bis(pinacolato)diborane試薬HCID 86639980Potassium tert-butoxide試薬HCID 1646813858-([2,2'-bipyridin]-5-yl)quinolin-2(1H)-one試薬HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium触媒HCID 8028Tetrahydrofuran溶媒

反応条件

温度
80 °C

出典と根拠

ORDレコード
ord-eb6d1b7c6fcb4f6987ce7b9722ad20c1
出典データセット
Borylation dataset from Roche

関連ノート

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