N-(2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl)benzamide → N-[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide

HRID 1491188

反応式

HRID 1491188 の反応式
O=C(Nc1c(F)c(F)c(C(F)(F)F)c(F)c1F)c1ccccc1>CC#N.CC(=O)O.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cc1ccc(S(=O)(=O)O)cc1.O=S(=O)(O)OOS(=O)(=O)O.[K].[Na].[Pd]>CC1(C)OB(c2ccccc2C(=O)Nc2c(F)c(F)c(C(F)(F)F)c(F)c2F)OC1(C)C

参加物

7

反応物 1

HCID 86708425N-(2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl)benzamide

生成物 1

HCID 101557522N-[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide収率 53%

試薬・触媒・溶媒 5

HCID 2733548Bis(pinacolato)diborane試薬HCID 24195884Sodium p-toluenesulfonate試薬HCID 43835029CID 43835029試薬HCID 587591933375-31-3触媒HCID 6342Acetonitrile溶媒

反応条件

温度
80 °C

出典と根拠

ORDレコード
ord-e3883b0f41cc48df8e630425b16a969f
出典データセット
Borylation dataset from Roche

関連ノート

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