Butylamine → HCID 178449171、化合物
反応式
[CH3:1][N:2]=[C:3]=[N:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[N:11]1[CH2:16][CH2:15][O:14][CH2:13][CH2:12]1.[CH2:17]([NH2:21])[CH2:18][CH2:19][CH3:20]>C(O)(C)(C)C>[CH2:17]([NH:21][C:3]([NH:2][CH3:1])=[N:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[N:11]1[CH2:16][CH2:15][O:14][CH2:13][CH2:12]1)[CH2:18][CH2:19][CH3:20]参加物
4
実験手順
A mixture of N-methyl-N'-(2-morpholinophenyl)carbodiimide (1 g), n-butylamine (0.5 g) and t-butanol (5 ml) was heated at 90°-95° C. for four hours. The solvent was removed by evaporation and the residue dissolved in dichloromethane (100 ml) and the resulting solution was washed with water, dried and filtered. Removal of the solvent gave 1-(n-butyl)-2-(2-morpholinophenyl)-3-methylguanidine which was converted into its monofumarate salt (m.p. 178°-179° C.).