Sodium borohydride → HCID 71014608、化合物
反応式
[F:1][C:2]1[CH:14]=[C:13]([CH:15]=[O:16])[CH:12]=[C:11]([O:17][CH3:18])[C:3]=1[O:4][CH2:5][C:6]([O:8][CH2:9][CH3:10])=[O:7].[BH4-].[Na+]>C1COCC1.O>[F:1][C:2]1[CH:14]=[C:13]([CH2:15][OH:16])[CH:12]=[C:11]([O:17][CH3:18])[C:3]=1[O:4][CH2:5][C:6]([O:8][CH2:9][CH3:10])=[O:7]参加物
5
実験手順
The compound was prepared according to general procedure F with Ethyl 2-(2-fluoro-4-formyl-6-methoxyphenoxy)acetate (1.4 mmol) in THF (20 ml) and water (20 ml) and NaBH4 (1.4 mmol). 220 mg of compound were obtained. This compound was used without further purification. 1H NMR (250 MHz, CDCl3): δ 1.33 (t, J=7.1 Hz, 3H), 3.90 (s, 3H), 4.28 (q, J=7.1 Hz, 2H), 4.65 (s, 2H), 4.71 (s, 2H) 6.95 (s, 1H), 6.76 (m, 2H). MS (ESI): m/z 538.8 [2M+Na]+
後処理
- customThe compound was prepared
出典と根拠
- ORDレコード
- ord-96844f6449dc45bd9861a4e051ba0738
- 出典データセット
- uspto-grants-2015_12
- 特許番号
- US09212196B2
反応ノート
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