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Sodium Carbonate → HCID 59722056、化合物

HRID 1513626
ノート
印刷プレビュー

反応式

HRID 1513626 の反応式
Br[C:2]1[N:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:5]=[C:4]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[N:3]=1.[C:20]1([C:26]2[C:27]3[C:32]([C:33]([C:43]4[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=4)=[C:34]4[C:39]=2[CH:38]=[C:37](B(O)O)[CH:36]=[CH:35]4)=[CH:31][CH:30]=[CH:29][CH:28]=3)[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.C(=O)([O-])[O-].[Na+].[Na+]>COCCOC.C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1>[C:20]1([C:26]2[C:39]3[C:34]([C:33]([C:43]4[CH:44]=[CH:45][CH:46]=[CH:47][CH:48]=4)=[C:32]4[C:27]=2[CH:28]=[C:29]([C:2]2[N:7]=[C:6]([C:8]5[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=5)[CH:5]=[C:4]([C:14]5[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=5)[N:3]=2)[CH:30]=[CH:31]4)=[CH:35][CH:36]=[CH:37][CH:38]=3)[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1
参加物実験手順後処理出典と根拠反応ノート

参加物

6

反応物 3

HCID 10340Sodium CarbonateHCID 17125192-Bromo-4,6-diphenylpyrimidineHCID 231602159,10-Diphenylanthracene-2-boronic Acid

生成物 1

HCID 59722056HCID 59722056、化合物収率 86%

試薬・触媒・溶媒 2

HCID 178418397HCID 178418397、化合物触媒
HCID 8071
1,2-Dimethoxyethane
溶媒

実験手順

2-Bromo-4,6-diphenylpyrimidine 3.4 g (11 mmol), 9,10-diphenylanthracene-2-boronic acid 4.9 g (13 mmol) and tetrakis(triphenylphosphine)palladium 0.25 g (0.22 mmol) were dissolved in 60 mL of 1,2-dimethoxyethane. A 2.0M sodium carbonate aqueous solution 30 mL was added thereto, and the solution was refluxed for 8 hours under argon atmosphere by heating. After finishing the reaction, the solution was filtered, and a solid matter obtained was washed with water, methanol and toluene to obtain 5.3 g (yield: 86%) of a greenish white solid matter. Mass spectral analysis of the above solid matter resulted in confirming that m/e was 560 versus a molecular weight of 560.23 and that it was the aimed compound 2.

後処理

  1. temperaturethe solution was refluxed for 8 hours under argon atmosphere
  2. temperatureby heating
  3. customthe reaction
  4. filtrationthe solution was filtered
  5. customa solid matter obtained
  6. washwas washed with water, methanol and toluene

出典と根拠

ORDレコード
ord-f1e56baf94584951b0df073405a623d4
出典データセット
uspto-grants-2012_07
DOI
10.6084/m9.figshare.5104873.v1
特許番号
US08217570B2

反応ノート

読み込み中…

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