Hydrogen Bromide → (R)-3-(3,4-Dihydroxyphenyl)-2-propylamine hydrobromide

反応式

C[O:2][C:3]1[CH:4]=[C:5]([CH2:11][C@H:12]([NH2:14])[CH3:13])[CH:6]=[CH:7][C:8]=1[O:9]C.[BrH:15]>>[BrH:15].[OH:2][C:3]1[CH:4]=[C:5]([CH2:11][C@H:12]([NH2:14])[CH3:13])[CH:6]=[CH:7][C:8]=1[OH:9]

参加物

反応物 2

HCID 260Hydrogen Bromide

HCID 117694083,4-Dma, (R)-

生成物 1

HCID 67643451(R)-3-(3,4-Dihydroxyphenyl)-2-propylamine hydrobromide

実験手順

A solution of (R)-3-(3,4-dimethoxyphenyl)-2-propylamine hydrochloride1 (500 mg, 2.15 mMol) in hydrogen bromide (48%, 5 ml) was stirred at 100° C. under an argon atmosphere for 20 hours. After cooling, the solvent was evaporated and the residue was dried giving the title compound.

後処理

temperatureAfter cooling
customthe solvent was evaporated
customthe residue was dried

出典と根拠

ORDレコード: ord-a3c93df638364213adea34d2adfb06d5
出典データセット: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05726165

反応ノート

読み込み中…

参加物