Hydrogen Bromide → (R)-3-(3,4-Dihydroxyphenyl)-2-propylamine hydrobromide

HRID 1523

反応式

HRID 1523 の反応式
C[O:2][C:3]1[CH:4]=[C:5]([CH2:11][C@H:12]([NH2:14])[CH3:13])[CH:6]=[CH:7][C:8]=1[O:9]C.[BrH:15]>>[BrH:15].[OH:2][C:3]1[CH:4]=[C:5]([CH2:11][C@H:12]([NH2:14])[CH3:13])[CH:6]=[CH:7][C:8]=1[OH:9]

参加物

3

反応物 2

HCID 260Hydrogen BromideHCID 117694083,4-Dma, (R)-

生成物 1

HCID 67643451(R)-3-(3,4-Dihydroxyphenyl)-2-propylamine hydrobromide

実験手順

A solution of (R)-3-(3,4-dimethoxyphenyl)-2-propylamine hydrochloride1 (500 mg, 2.15 mMol) in hydrogen bromide (48%, 5 ml) was stirred at 100° C. under an argon atmosphere for 20 hours. After cooling, the solvent was evaporated and the residue was dried giving the title compound.

後処理

  1. temperatureAfter cooling
  2. customthe solvent was evaporated
  3. customthe residue was dried

出典と根拠

ORDレコード
ord-a3c93df638364213adea34d2adfb06d5
出典データセット
uspto-grants-1998_03
特許番号
US05726165

関連ノート

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