N-bromobutanimide → Methyl 5-(bromomethyl)-2-methoxybenzoate

HRID 1531917

反応式

HRID 1531917 の反応式
[CH3:1][O:2][C:3](=[O:13])[C:4]1[CH:9]=[C:8]([CH3:10])[CH:7]=[CH:6][C:5]=1[O:11][CH3:12].[Br:14]N1C(=O)CCC1=O>C1C=CC=CC=1>[Br:14][CH2:10][C:8]1[CH:7]=[CH:6][C:5]([O:11][CH3:12])=[C:4]([CH:9]=1)[C:3]([O:2][CH3:1])=[O:13]

参加物

4

反応物 2

HCID 67184N-bromobutanimideHCID 10241396Methyl 2-methoxy-5-methylbenzoate

生成物 1

HCID 19744340Methyl 5-(bromomethyl)-2-methoxybenzoate

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

A mixture of 2-methoxy-5-methylbenzoic acid methyl ester (J.Chem.Soc.Perkin Trans.1, 1994, 1125) (1.47 g) and N-bromosuccinimide (1.45 g) in benzene (15 ml) was irradiated under a 500 W halogen lamp for 3 hours. The solvent was evaporated and the residue triturated with diethyl ether. The succinimide was filtered off and the filtrate evaporated.

後処理

  1. customThe solvent was evaporated
  2. customthe residue triturated with diethyl ether
  3. filtrationThe succinimide was filtered off
  4. customthe filtrate evaporated

出典と根拠

ORDレコード
ord-cc5a220a1f5644198b9e4917cab8fd4f
出典データセット
uspto-grants-2001_03
特許番号
US06200981B1

関連ノート

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