Dichloromethane → 2-[[1-(4-Methoxy-2,6-dimethylphenyl)sulfonylpiperidin-2-yl]methoxy]-1-[4-pyridin-4-yl-4-(2-pyrrolidin-1-ylethoxy)piperidin-1-yl]ethanone
反応式
[CH2:79]([Cl:80])[Cl:81].[CH3:20][O:21][c:22]1[cH:23][c:24]([CH3:44])[c:25]([S:29](=[O:30])(=[O:31])[N:32]2[CH:33]([CH2:38][O:39][CH2:40][C:41](=[O:42])[OH:43])[CH2:34][CH2:35][CH2:36][CH2:37]2)[c:26]([CH3:28])[cH:27]1.[CH:1]([N:2]([CH2:3][CH3:4])[CH:5]([CH3:6])[CH3:7])([CH3:8])[CH3:9].[F:72][C:73]([F:74])([F:75])[C:76]([OH:77])=[O:78].[OH:10][n:11]1[c:12]2[c:13]([cH:14][cH:15][cH:16][cH:17]2)[n:18][n:19]1.[n:45]1[cH:46][cH:47][c:48]([C:51]2([O:64][CH2:65][CH2:66][N:67]3[CH2:68][CH2:69][CH2:70][CH2:71]3)[CH2:52][CH2:53][N:54]([C:57]([O:58][C:59]([CH3:60])([CH3:61])[CH3:62])=[O:63])[CH2:55][CH2:56]2)[cH:49][cH:50]1>>[CH3:20][O:21][c:22]1[cH:23][c:24]([CH3:44])[c:25]([S:29](=[O:30])(=[O:31])[N:32]2[CH:33]([CH2:38][O:39][CH2:40][C:41](=[O:43])[N:54]3[CH2:53][CH2:52][C:51]([c:48]4[cH:47][cH:46][n:45][cH:50][cH:49]4)([O:64][CH2:65][CH2:66][N:67]4[CH2:68][CH2:69][CH2:70][CH2:71]4)[CH2:56][CH2:55]3)[CH2:34][CH2:35][CH2:36][CH2:37]2)[c:26]([CH3:28])[cH:27]1参加物
7
反応物 6
HCID 6344Dichloromethane
HCID 6422Trifluoroacetic acid
HCID 757711-Hydroxybenzotriazole
HCID 81531Diisopropylethylamine
HCID 574368002-((1-(4-Methoxy-2,6-dimethylphenylsulfonyl)piperidin-2-yl)methoxy)acetic acid
HCID 57916270tert-Butyl 4-(pyridin-4-yl)-4-(2-(pyrrolidin-1-yl)ethoxy)piperidine-1-carboxylate