Nitric Acid → HCID 13535752、化合物
反応式
[N+:1]([O-:4])([OH:3])=[O:2].C(OC(=O)C)(=O)C.O[C@H:13]1[CH2:17][C:16](=[O:18])[C:15]([CH2:19][CH:20]=[CH2:21])=[C:14]1[CH3:22]>C(Cl)(Cl)Cl>[CH3:22][C:14]1[C@@H:13]([O:2][N+:1]([O-:4])=[O:3])[CH2:17][C:16](=[O:18])[C:15]=1[CH2:19][CH:20]=[CH2:21]参加物
5
実験手順
Into a mixed solution of 8 g of fuming nitric acid and 24 g of acetic anhydride, kept at a temperature of -5° to 10° C., was added dropwise 6 g of (S)-4-hydroxy-3-methyl-2-(2-propenyl)-2-cyclopenten-1-one ([α]D23 : +10.3° (C=1.17, in chloroform), (R)-isomer/(S)-isomer=15.7/84.3). Thereafter, with the same operations as in Example 1, 7.56 g of crude (S)-3-methyl-4-nitroxy-2-(2-propenyl)-2-cyclopenten-1-one was obtained.
後処理
- customkept at a temperature of -5° to 10° C.
出典と根拠
- ORDレコード
- ord-a35de2d6d05e49e3ae8fe4031621f605
- 出典データセット
- uspto-grants-1985_11
- 特許番号
- US04552703
反応ノート
読み込み中…