Sodium hydride → HCID 19759871、化合物
反応式
[CH3:1][C:2]1([C:12]([OH:14])=[O:13])[S:9](=[O:11])(=[O:10])[C:5]2[S:6][CH:7]=[CH:8][C:4]=2[CH2:3]1.S1(=O)(=O)C2SC=CC=2[CH2:17][CH:16]1C(O)=O.[H-].[Na+].C(I)CC>CN(C=O)C>[CH2:1]([C:2]1([C:12]([OH:14])=[O:13])[S:9](=[O:11])(=[O:10])[C:5]2[S:6][CH:7]=[CH:8][C:4]=2[CH2:3]1)[CH2:16][CH3:17]参加物
6
実験手順
The title compound was prepared in substantially the same way was 2,3-dihydro-2-methylthieno[2,3-b]thiophene-2-carboxylic acid-1,1-dioxide. Thus, 2,3-dihydrothieno[2,3-b]thiophene-2-carboxylic acid-1,1-dioxide (10.5 g, 0.048 mol) when reacted with NaH (5.76 g, 60% dispersion in oil) and n-propyl iodide (14 mL, 0.047 mol) in DMF (200 mL) gave the title compound as a gum (11.3 g, 90%).
後処理
- customThe title compound was prepared in substantially the same way
出典と根拠
- ORDレコード
- ord-cef4fcc76fc243c6b8fbda721f093ce5
- 出典データセット
- uspto-grants-1993_06
- 特許番号
- US05216020
反応ノート
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