Methyl iodide → N,N-Diethyl-2-methoxy-N-methylethan-1-aminium iodide

HRID 1593346ノート

反応式

HRID 1593346 の反応式
[CH3:1][O:2][CH2:3][CH2:4][N:5]([CH2:8][CH3:9])[CH2:6][CH3:7].[CH3:10][I:11]>O1CCCC1>[I-:11].[CH3:1][O:2][CH2:3][CH2:4][N+:5]([CH2:8][CH3:9])([CH2:6][CH3:7])[CH3:10]

参加物

4

反応物 2

HCID 6328Methyl iodideHCID 113555002-methoxyethyldiethylamine

生成物 1

HCID 71374868N,N-Diethyl-2-methoxy-N-methylethan-1-aminium iodide

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

Next, 8.24 g of the 2-methoxyethyldiethylamine was dissolved in 10 ml of tetrahydrofuran (Wako Pure Chemical Industries), following which 4.0 ml of methyl iodide (Wako Pure Chemical Industries) was added under ice cooling. After 30 minutes, the mixture was removed from the ice bath and stirred overnight at room temperature. The solvent in the resulting reaction mixture was then driven off by vacuum distillation, and the resulting solids were recrystallized from an ethanol (Wako Pure Chemical Industries)-tetrahydrofuran system, yielding 16 g of 2-methoxyethyldiethylmethylammonium iodide.

後処理

  1. additionwas added under ice cooling
  2. customthe mixture was removed from the ice bath
  3. customThe solvent in the resulting reaction mixture
  4. distillationwas then driven off by vacuum distillation
  5. customthe resulting solids were recrystallized from an ethanol (Wako Pure Chemical Industries)-tetrahydrofuran system

出典と根拠

ORDレコード
ord-c874a9245ca94705b04cdafbe3025f31
出典データセット
uspto-grants-2007_11
特許番号
US07297289B2

反応ノート

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