Phenylpropanolamine → (1S,2R)-2-amino-1-phenylpropan-1-ol

HRID 1595956

反応式

HRID 1595956 の反応式
[CH3:1][C@H:2]([NH2:11])[C@H:3]([OH:10])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[BH4-].[Na+]>C(O)C>[CH3:1][C@@H:2]([NH2:11])[C@@H:3]([OH:10])[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1

参加物

4

実験手順

As shown in the scheme above, (1R, 2S)-(−)- norephedrine is reacted with an optionally substituted benzaldehyde by refluxing in ethanol, and reducing the product of that reaction with sodium borohydride at ambient temperature to produce the desired norephedrine derivative compound.

出典と根拠

ORDレコード
ord-b28c151d057f4f0bbcfc10c69ab8201e
出典データセット
uspto-grants-2001_09
特許番号
US06288233B1

関連ノート

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