Sodium hydride → (2R)-4-(3-Pyridyl)-1-(6-(3,3,3-trifluoropropoxy)naphthalen-2-yloxy)-2-butanol

反応式

[OH:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([O:12][CH2:13][CH2:14][C:15]([F:18])([F:17])[F:16])[CH:8]=2)[CH:3]=1.C1(C)C=CC(S(O[CH2:29][C@H:30]([O:39][Si](C(C)(C)C)(C)C)[CH2:31][CH2:32][C:33]2[CH:34]=[N:35][CH:36]=[CH:37][CH:38]=2)(=O)=O)=CC=1.[H-].[Na+].O.[F-].C([N+](CCCC)(CCCC)CCCC)CCC>CN(C)C=O.O1CCCC1.O>[N:35]1[CH:36]=[CH:37][CH:38]=[C:33]([CH2:32][CH2:31][C@@H:30]([OH:39])[CH2:29][O:1][C:2]2[CH:11]=[CH:10][C:9]3[C:4](=[CH:5][CH:6]=[C:7]([O:12][CH2:13][CH2:14][C:15]([F:16])([F:17])[F:18])[CH:8]=3)[CH:3]=2)[CH:34]=1