Oxalyl chloride → HCID 22168546、化合物

HRID 1607865ノート

反応式

HRID 1607865 の反応式
[C:1]([CH2:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][C:12]([O:14][CH3:15])=[O:13])=[CH:7][CH:6]=1)(O)=[O:2].C(Cl)(=O)C([Cl:19])=O>O1CCCC1>[C:12]([CH2:11][C:8]1[CH:9]=[CH:10][C:5]([CH2:4][C:1]([Cl:19])=[O:2])=[CH:6][CH:7]=1)([O:14][CH3:15])=[O:13]

参加物

4

反応物 2

HCID 65578Oxalyl chlorideHCID 14219918HCID 14219918、化合物

生成物 1

HCID 22168546HCID 22168546、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

反応条件

温度
45 °C

実験手順

A 3.04 g portion of methyl 4-carboxymethylphenylacetate, prepared above, was dissolved in 50 mL of anhydrous tetrahydrofuran. After the addition of2.5 mL oxalyl chloride, the mixture was stirred for 4 hours. The solvents were evaporated under a stream of dry nitrogen as the flask was warmed to 45° C. Any remaining solvent or oxalyl chloride was then removed under high vacuum; the product was used without further purification.

後処理

  1. customThe solvents were evaporated under a stream of dry nitrogen as the flask
  2. customAny remaining solvent or oxalyl chloride was then removed under high vacuum
  3. customthe product was used without further purification

出典と根拠

ORDレコード
ord-8a8e2af98bb542d2b303768ccd815052
出典データセット
uspto-grants-1989_09
特許番号
US04868132

反応ノート

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