Dichloromethane → (2',4'-Difluoro-biphenyl-4-yl)-(8-pyrimidin-2-yl-8-aza-bicyclo[3.2.1]oct-3-yl)-methanone

反応式

Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH:10]2[CH2:16][CH:15]3[N:17]([C:18]4[N:23]=[CH:22][CH:21]=[CH:20][N:19]=4)[CH:12]([CH2:13][CH2:14]3)[CH2:11]2)=[O:9])=[CH:4][CH:3]=1.[F:24][C:25]1[CH:30]=[C:29]([F:31])[CH:28]=[CH:27][C:26]=1B(O)O.ClCCl.[O-]P([O-])([O-])=O.[K+].[K+].[K+]>C(OCC)(=O)C.[OH-].[Na+].C1C=CC(P([C]2[CH][CH][CH][CH]2)C2C=CC=CC=2)=CC=1.C1C=CC(P([C]2[CH][CH][CH][CH]2)C2C=CC=CC=2)=CC=1.Cl[Pd]Cl.[Fe].O>[F:24][C:25]1[CH:30]=[C:29]([F:31])[CH:28]=[CH:27][C:26]=1[C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH:10]2[CH2:11][CH:12]3[N:17]([C:18]4[N:19]=[CH:20][CH:21]=[CH:22][N:23]=4)[CH:15]([CH2:14][CH2:13]3)[CH2:16]2)=[O:9])=[CH:4][CH:3]=1