HCID 86632924、化合物 → HCID 86632925、化合物

HRID 1628585ノート

反応式

HRID 1628585 の反応式
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([N+:10]([O-])=O)[C:5]=1[NH:13][CH2:14][CH2:15][CH2:16][NH:17][C:18](=[O:24])[O:19][C:20]([CH3:23])([CH3:22])[CH3:21])([O-])=O>[Pd].O1CCCC1>[NH2:10][C:6]1[CH:7]=[CH:8][CH:9]=[C:4]([NH2:1])[C:5]=1[NH:13][CH2:14][CH2:15][CH2:16][NH:17][C:18](=[O:24])[O:19][C:20]([CH3:22])([CH3:21])[CH3:23]

参加物

4

反応物 1

HCID 86632924HCID 86632924、化合物

生成物 1

HCID 86632925HCID 86632925、化合物収率 98%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 8028Tetrahydrofuran溶媒

実験手順

Under hydrogen gas atmosphere, a mixture of tert-butyl {3-[(2,6-dinitrophenyl)amino]propyl}carbamate (6.79 g, 20.0 mmol) and 10% palladium on carbon (50% wet, 1.4 g) in tetrahydrofuran (200 mL) was stirred at room temperature for 2 h. The reaction mixture was filtered and concentrated in vacuo to give the title compound as an orange oil (5.47 g, 19.5 mmol, 98%).

後処理

  1. filtrationThe reaction mixture was filtered
  2. concentrationconcentrated in vacuo

出典と根拠

ORDレコード
ord-3886cdc09d8546fdbf8af8f33658b869
出典データセット
uspto-grants-2014_07
特許番号
US08785460B2

反応ノート

読み込み中…