1,3,5-Trichlorobenzene → 3,5-Dichlorophenylhydrazine

HRID 1635692

反応式

HRID 1635692 の反応式
[Cl:1][C:2]1[CH:7]=[C:6](Cl)[CH:5]=[C:4]([Cl:9])[CH:3]=1.O.[NH2:11][NH2:12]>N1C=CC=CC=1>[Cl:1][C:2]1[CH:7]=[C:6]([NH:11][NH2:12])[CH:5]=[C:4]([Cl:9])[CH:3]=1

参加物

4

反応物 2

HCID 79501,3,5-TrichlorobenzeneHCID 24654Hydrazine hydrate (1:1)

生成物 1

HCID 6004693,5-Dichlorophenylhydrazine収率 60%

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

反応条件

温度
180 °C

実験手順

A mixture of 1,3,5-trichlorobenzene (2.53 g), hydrazine hydrate (3.48 g, 5 molar equivalents) and pyridine (12 ml) was heated in an autoclave (purged with argon) for 6 hours at 180° C. The mixture was cooled, the excess hydrazine decanted and the organic phase evaporated in vacuo to give the title compound in 60% yield. It was shown that 65% of the starting material had been consumed, thus indicating that the reaction had occurred with high selectivity.

後処理

  1. temperatureThe mixture was cooled
  2. customthe excess hydrazine decanted
  3. customthe organic phase evaporated in vacuo

出典と根拠

ORDレコード
ord-3e6a2dccd2424f91bb0356d383f5ee0e
出典データセット
uspto-grants-2003_01
特許番号
US06509503B1

関連ノート

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