Acetone → Ethanol, 2-[(1-methylethyl)(phenylmethyl)amino]-

HRID 1647552ノート

反応式

HRID 1647552 の反応式
[NH2:1][CH2:2][CH2:3][OH:4].[CH:5](=O)[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.C(O)C.[H][H].[CH3:18][C:19]([CH3:21])=O>[Pt]>[CH3:18][CH:19]([N:1]([CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[CH2:2][CH2:3][OH:4])[CH3:21]

参加物

7

反応物 5

HCID 180AcetoneHCID 240BenzaldehydeHCID 700EthanolamineHCID 702EthanolHCID 178418361HCID 178418361、化合物2 回

生成物 1

HCID 11084730Ethanol, 2-[(1-methylethyl)(phenylmethyl)amino]-

試薬・触媒・溶媒 1

HCID 23939Platinum触媒2 回

実験手順

A process according to claim 1 for preparing the compound of the formula ##STR26## which comprises: (a) alkylating 2-aminoethanol using benzaldehyde and ethanol in the presence of a platinum catalyst and hydrogen followed by reductive alkylation using acetone in the presence of a platinum catalyst and hydrogen to give 2-[(1-methylethyl)(phenylmethyl) amino]ethanol;

後処理

  1. customA process according to claim 1 for preparing the compound of the formula ##STR26## which

出典と根拠

ORDレコード
ord-876bb00f75fe4c3094bc14ab7808061c
出典データセット
uspto-grants-1995_07
特許番号
US05432284

反応ノート

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