Hydrochloric Acid → Acetophenone

The aqueous layer and the 10% hydrochloric acid washings were joined and the joined solution was mixed with a 10% sodium hydroxide solution (30 ml) to adjust the pH to about 11 and extracted with ethyl acetate (50 ml×3). The extract was washed with a saturated saline solution (50 ml×3), dried and then ethyl acetate was distilled off to obtain a mixture of N-methylephedrine and N-ethylaniline. Yield: 2.4 g (100%). Said two substances can be recovered, separately by distilling the mixture under reduced pressure.

1. extractionextracted with ethyl acetate (50 ml×3)
2. washThe extract was washed with a saturated saline solution (50 ml×3)
3. customdried
4. distillationethyl acetate was distilled off
5. customto obtain
6. customcan be recovered
7. distillationseparately by distilling the mixture under reduced pressure

ORDレコード

ord-688971b6375e4e3099da4d666833e252

出典データセット

uspto-grants-1983_11

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US04418218