Water → 2-Iodobenzohydrazide
反応式
[I:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4](O)=[O:5].C(N1C=CN=C1)(N1C=CN=C1)=O.[NH2:23][NH2:24].O>ClCCl>[I:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:23][NH2:24])=[O:5]参加物
6
実験手順
2-Iodobenzoic acid (3.00 g, 12.1 mmol) was dissolved in dichloromethane (150 mL), and the mixture was stirred at room temperature for 2 hours after adding 1,1′-carbonyldiimidazole (2.16 g, 13.3 mmol). Thereafter, hydrazine.monohydrate (3.52 mL, 72.6 mmol) was added to the mixture, and the mixture was stirred at room temperature for 3 hours. Water was added after concentrating the mixture under reduced pressure, and the precipitated solid was collected by filtration, and dried under reduced pressure to give 2-iodobenzohydrazide (2.81 g, 89%).
後処理
- stirringthe mixture was stirred at room temperature for 3 hours
- concentrationafter concentrating the mixture under reduced pressure
- filtrationthe precipitated solid was collected by filtration
- customdried under reduced pressure
出典と根拠
- ORDレコード
- ord-d9a25951b48047ef8cd1d299710300e6
- 出典データセット
- uspto-grants-2011_08
- 特許番号
- US07998954B2
反応ノート
読み込み中…