Water → Acetophenone

HRID 1681449

反応式

HRID 1681449 の反応式
[CH2:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1)[CH3:2].O.S([O-])([O-])=[O:11].[Na+].[Na+].[N+]([O-])([O-])=O.[Pb+2].[N+]([O-])([O-])=O>>[C:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1)(=[O:11])[CH3:2]

参加物

5

反応物 4

HCID 962WaterHCID 7500EthylbenzeneHCID 24437Sodium SulfiteHCID 24924Lead nitrate

生成物 1

HCID 7410Acetophenone収率 95%

実験手順

Ten millimoles of ethylbenzene were heated at 400° C. for 1 hour with 1.35 ml of water containing 20 millimoles of sodium sulfite and 10 millimoles of lead nitrate. On cooling, a suspension of black precipitate was observed. The reaction product was extracted with ether and the ether layer was dried over Na2SO4 and concentrated to yield acetophenone in more than 95% yield. Acetophenone was confirmed by NMR and gas chromatographic techniques.

後処理

  1. temperatureOn cooling
  2. additiona suspension of black precipitate
  3. extractionThe reaction product was extracted with ether
  4. dry with materialthe ether layer was dried over Na2SO4
  5. concentrationconcentrated

出典と根拠

ORDレコード
ord-f2ef92410e4545f4b0b37e77be1d5962
出典データセット
uspto-grants-1992_12
特許番号
US05171880

関連ノート

読み込み中…