1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide → Tert-butyl 4-(6-(5-(3-fluoro-2-(2-hydroxy-2-phenylpentylcarbamoyl)pyridin-4-ylthio)thiazol-2-ylamino)pyridin-3-ylamino)piperidine-1-carboxylate

反応式

[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH:11]([NH:14][C:15]2[CH:16]=[CH:17][C:18]([NH:21][C:22]3[S:23][C:24]([S:27][C:28]4[CH:33]=[CH:32][N:31]=[C:30]([C:34](O)=[O:35])[C:29]=4[F:37])=[CH:25][N:26]=3)=[N:19][CH:20]=2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[NH2:38][CH2:39][C:40]([C:45]1[CH:50]=[CH:49][CH:48]=[CH:47][CH:46]=1)([OH:44])[CH2:41][CH2:42][CH3:43].CCN=C=NCCCN(C)C.C1C=CC2N(O)N=NC=2C=1.CCN(C(C)C)C(C)C>CN1C(=O)CCC1.O>[F:37][C:29]1[C:30]([C:34](=[O:35])[NH:38][CH2:39][C:40]([OH:44])([C:45]2[CH:46]=[CH:47][CH:48]=[CH:49][CH:50]=2)[CH2:41][CH2:42][CH3:43])=[N:31][CH:32]=[CH:33][C:28]=1[S:27][C:24]1[S:23][C:22]([NH:21][C:18]2[N:19]=[CH:20][C:15]([NH:14][CH:11]3[CH2:12][CH2:13][N:8]([C:6]([O:5][C:1]([CH3:2])([CH3:3])[CH3:4])=[O:7])[CH2:9][CH2:10]3)=[CH:16][CH:17]=2)=[N:26][CH:25]=1