Methyl 3-(2-chlorophenyl)propanoate → 3-(2-Chlorophenyl)propanoic acid

HRID 1701338

反応式

HRID 1701338 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH2:9][C:10]([O:12]C)=[O:11]>[OH-].[Na+]>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH2:9][C:10]([OH:12])=[O:11]

参加物

3

反応物 1

HCID 18913495Methyl 3-(2-chlorophenyl)propanoate

生成物 1

HCID 956763-(2-Chlorophenyl)propanoic acid

試薬・触媒・溶媒 1

HCID 14798Sodium Hydroxide溶媒

実験手順

Methyl 3-(2-chlorophenyl)propionate was refluxed in 10% aqueous sodium hydroxide (1 l.) for two hours and the reaction mixture was cooled, acidified and filtered. The filter cake was dissolved in hot aqueous sodium bicarbonate and filtered. The filtrate was acidified and filtered to yield 3-(2-chlorophenyl)propionic acid.

後処理

  1. temperaturethe reaction mixture was cooled
  2. filtrationfiltered
  3. dissolutionThe filter cake was dissolved in hot aqueous sodium bicarbonate
  4. filtrationfiltered
  5. filtrationfiltered

出典と根拠

ORDレコード
ord-50b52fd89ee74f889f0ab0f9aeecf7b9
出典データセット
uspto-grants-1980_03
特許番号
US04192888

関連ノート

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