Benzenamine, 4-methyl-, hydrochloride (1:1) → 1,2-Ethanediamine, N-(4-methylphenyl)-
反応式
Cl.[CH3:2][C:3]1[CH:9]=[CH:8][C:6]([NH2:7])=[CH:5][CH:4]=1.O1[CH2:14][CH2:13][NH:12]C1=O>COCCOCCO>[CH3:2][C:3]1[CH:9]=[CH:8][C:6]([NH:7][CH2:14][CH2:13][NH2:12])=[CH:5][CH:4]=1参加物
4
反応条件
- 温度
- 170 °C
実験手順
A mixture of 4-methylaniline hydrochloride (15.0 g, 0.10 mole), 2-oxazolidinone (8.7 g, 0.10 mole) and 40 ml of 2-(2-methoxyethoxy)ethanol was heated in an oil bath to 170° C. for four hours. On cooling to room temperature, a solid formed. Workup as described in Examples 1 and 8, followed by distillation at 110° C. to 120° C. (1.5 mm Hg) gave a 76 percent yield of the material as a clear liquid which slowly solidified on standing at ambient temperatures to a low-melting solid.
後処理
- temperatureOn cooling to room temperature
- customa solid formed
- distillationfollowed by distillation at 110° C. to 120° C. (1.5 mm Hg)
出典と根拠
- ORDレコード
- ord-dba9b8a3b28347a091c579c35f9d76c2
- 出典データセット
- uspto-grants-1983_04
- 特許番号
- US04381401
反応ノート
読み込み中…