Thionyl Chloride → Benzenamine, N-(3-chloropropyl)-2-nitro-
反応式
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][CH2:11][CH2:12][CH2:13]O)([O-:3])=[O:2].S(Cl)([Cl:17])=O>ClC(Cl)Cl>[Cl:17][CH2:13][CH2:12][CH2:11][NH:10][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[N+:1]([O-:3])=[O:2]参加物
4
実験手順
To a stirred mixture of 39.2 parts of 3-(2-nitrophenyl)amino-1-propanol and 225 parts of trichloromethane are added dropwise 35.7 parts of sulfinyl chloride (exothermic reaction: the temperature rises to 45° C.). Upon completion, stirring is continued for 6 hours at reflux temperature. The reaction mixture is evaporated, yielding 43 parts (100%) of N-(3-chloropropyl)-2-nitrobenzenamine as a residue.
後処理
- customexothermic reaction
- customrises to 45° C.
- temperatureat reflux temperature
- customThe reaction mixture is evaporated
出典と根拠
- ORDレコード
- ord-8d79f4869f564d02b208dacf16d0cf5d
- 出典データセット
- uspto-grants-1978_11
- 特許番号
- US04126687
反応ノート
読み込み中…