Pyridine → 2-Hydrazino-5-phenylpyrimidine
反応式
Cl[C:2]1[N:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:4][N:3]=1.N1C=CC=CC=1.O.[NH2:21][NH2:22]>O>[NH:21]([C:2]1[N:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:4][N:3]=1)[NH2:22]参加物
5
実験手順
To a solution of 5.4 g. of 2-chloro-5-phenylpyrimidine in 25 ml. of pyridine is added 25 ml. of hydrazine hydrate. The mixture is heated on a steam bath for one hour with occasional swirling. Water is added and the material that is separated is collected and crystallized from methanol to give 4.5 g. of the product of the Example, m.p. 155° C.
後処理
- temperatureThe mixture is heated on a steam bath for one hour
- customthe material that is separated
- customis collected
- customcrystallized from methanol
- customto give 4.5 g
出典と根拠
- ORDレコード
- ord-0dedac35560640c38892fcf397a01082
- 出典データセット
- uspto-grants-1980_06
- 特許番号
- US04209621
反応ノート
読み込み中…